Research Involving Animal Subjects

Federal regulations and professional guidelines are in place to assure the responsible use of animals in research. Researchers who expect to use or study living animals are responsible for: knowing what activities are subject to regulation; understanding and following the rules for project approval; obtaining appropriate training; and maintaining compliance through all stages of a project. (Office of Research Integrity)

Resources in this section will address:

  • What federal regulations apply to the use and care of animals in research?
  • What is the role of an Institutional Animal Care and Use Committee (IACUC)?
  • How do the three principles of "Replacement, Reduction, and Refinement" (Russell and Burch, 1959) act as a guide for the humane use of animals in research?