Federal regulations and professional guidelines are in place to assure the responsible use of animals in research. Researchers who expect to use or study living animals are responsible for: knowing what activities are subject to regulation; understanding and following the rules for project approval; obtaining appropriate training; and maintaining compliance through all stages of a project. (Office of Research Integrity)

Resources in this section will address:

  • What federal regulations apply to the use and care of animals in research?
  • What is the role of an Institutional Animal Care and Use Committee (IACUC)?
  • How do the three principles of "Replacement, Reduction, and Refinement" (Russell and Burch, 1959) act as a guide for the humane use of animals in research?